Immunohistochemical localisation of advanced glycation end products in pulmonary fibrosis

Advanced glycation end-products and receptor for advanced glycation end-products expression in patients with idiopathic pulmonary fibrosis and NSIP.

Advanced glycation end products (AGEs) are associated with the pathogenesis of various diseases. AGEs induce excess accumulation of extracellular matrix and expression of profibrotic cytokines. In addition, studies on receptor for advanced glycation end products (RAGE) have shown that the ligand-RAGE interaction activates several intracellular signaling cascades associated with several fibrotic...

Advanced glycation end products

Aging is the progressive accumulation of damage to an organism over time leading to disease and death. Aging research has been very intensive in the last years aiming at characterizing the pathophysiology of aging and finding possibilities to fight age-related diseases. Various theories of aging have been proposed. In the last years advanced glycation end products (AGEs) have received particula...

The Role of the Receptor for Advanced Glycation End Products (RAGE) in idiopathic Pulmonary Fibrosis

Advanced glycation end products, soluble receptor for advanced glycation end products, and risk of colorectal cancer.

BACKGROUND Advanced glycation end products (AGE) accumulate in human tissue proteins during aging, particularly under hyperglycemia conditions. AGEs induce oxidative stress and inflammation via the receptor for AGEs (RAGE) and soluble RAGE (sRAGE) can neutralize the effects mediated by RAGE-ligand engagement. METHODS We examined the association between N(ε)-(carboxymethyl)lysine (CML), a prom...

Salvia reuterana Extract Prevents Formation of Advanced Glycation End Products: An In Vitro Study

       In this study, we examined the antioxidant activities of methanolic extract of three endemic species of Salvia from Iran (S. lachno...